Why the study?
The review was conducted to establish the incidence of cardiac arrhythmia following the prescription of a fluoroquinolone antibiotic.
What is the incidence of cardiac arrhythmia in adult patients with acute infection prescribed fluoroquinolones?
What is the incidence of cardiac arrhythmia in adult patients with acute infection prescribed fluoroquinolones?
The incidence of cardiac arrhythmia in adult patients prescribed fluoroquinolones for acute infection is low (<3%), though current estimates lack precision.
Answers are grounded in this paper and cite their sources.
Alerts clinicians to potential arrhythmia risk with fluoroquinolones; leaves open need for confirmatory prospective trials.
A shortcut review was carried out to establish the incidence of arrhythmia after prescription of a fluoroquinolone antibiotic. 332 papers were found using the reported searches, of which 14 presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. It is concluded that the incidence of arrhythmia after prescription of a fluoroquinolone antibiotic is low (<3%), but estimates are imprecise.
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Chan et al. (2019) studied this question.
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