Why the study?
Despite advances in RT techniques, cardiotoxicity remains an important side effect in breast cancer treatment, requiring summarized guidance on incidence, risk factors, mechanisms, and follow-up.
Radiotherapy for breast cancer is associated with significant cardiovascular toxicity, most notably atherosclerosis, highlighting the need for baseline evaluation, risk stratification, and interdisciplinary management as recommended by cardio-oncology guidelines.
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RT cardiotoxicity monitoring in breast cancer may aid risk stratification; leaves open optimal prevention and long-term outcome data.
The number of patients diagnosed with breast cancer and cardiovascular disease is continuously rising. Treatment options for breast cancer have greatly evolved, but radiotherapy (RT) still has a key role in it. Despite many advances in RT techniques, cardiotoxicity is one of the most important side effects. The new cardio-oncology guidelines recommend a baseline evaluation, risk stratification and follow-up of these patients. Cardiotoxicity induced by RT can be represented by almost all forms of cardiovascular disease, with atherosclerosis being the most frequent. An interdisciplinary team should manage these patients, in order to have maximum therapeutic effect and minimum cardiovascular toxicity. This review will summarize the current incidence, risk factors, mechanisms and follow-up of RT-induced cardiovascular toxicity.
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Ştefan et al. (2023) studied this question.
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