Managing ischemic and bleeding risk in cancer patients presenting with acute coronary syndromes: A challenge accepted?

Cardiovascular disease (CVD) and cancer are the leading causes of death in developed countries.Improvements in early detection and major advances in cancer treatments have led to a growing number of survivors.However, cancer patients, including survivors, have a high risk for CVD that can be explained by multiple factors, including toxicity of cancer treatments (old and new drugs, chest radiotherapy), shared cardiovascular risk factors like age, genetics, obesity, smoking and lifestyle, and older age with higher burden of pre-existing CVD.Coronary artery disease is a frequent comorbidity in patients being treated for cancer and in survivors.Patients with cancer are unique in that they are a diverse group of patients who are at increased risk of both bleeding and ischemic complications, depending on the type and stage of cancer, and require a highly individualized