p. 880) on the technique employed by Dr.R. E. Loder.I have been concerned with this subject for the past 20 years.Before the introduction of muscle relaxants, when ether was used as the main agent in all anaesthetics requiring muscular relaxation, in order to avoid the unpleasant after-effects of ether I began to use a combination of light anaesthesia with Pentothal (thiopentone), N20, and oxygen with various regional blocks (intercostal for abdominal operations, para- vertebral for herniotomies, and pre-sacral for haemorrhoidectomy).When curare and like
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James Todd (1965) studied this question.