Why the study?
With the global prevalence of obesity rising and demand for efficacious treatments growing, the safety and efficacy of neuromodulation therapies needed evaluation.
Do neuromodulation therapies reduce body weight in patients with obesity?
Population
3,042 participants across 60 trials with obesity
Comparison
Neuromodulation therapies (DBS, TMS, tDCS, PENS, VNS, GES)
Design
Systematic review using PRISMA guidelines
Authors
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Neuromodulation shows preliminary signals for weight loss; leaves open its clinical role pending larger confirmatory RCTs.
Do neuromodulation therapies reduce body weight in patients with obesity?
Current evidence from double-blinded RCTs does not support a striking reduction in body weight with neuromodulation therapies in patients with obesity.
Gouveia et al. (2021) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: