Two transcriptional regulators in the bacterium Ralstonia solanacearum (VsrAD and PhcA) that play a central role for virulence were shown to affect secondary metabolism as well; this led to the identification of a new natural product, ralfuranone. The results shed light on the regulation and biosynthetic capacities for secondary metabolism of this plant pathogen.
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Schneider et al. (2009) studied this question.
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