Successful Preoperative Radiotherapy for Neglected Shoulder Liposarcoma: A Retrospective Case Report

Figures

• 

  Figure 1. MRI of right shoulder: preradiotherapy treatment in the frontal plane.

• 

  Figure 2. CT planning of tumour in sagittal, frontal, and transverse planes.

• 

  Figure 3. Tumour staging via FDG-PET in sagittal and frontal planes.

• 

  Figure 4. Haematoxylin-eosin stain. (a) ×400 magnification. Viable tumour composed of variably sized adipocytes and scattered pleomorphic spindle cells in fibromyxoid stroma. (b) ×100 magnification. Tumour includes necrotic area with reduced cellularity. (c) ×40 magnification. Dedifferentiated liposarcoma showing discrete areas of nonadipocytic sarcomatous components (stained pink).

• 

  Figure 5. Fluorescence in situ hybridization. The CytoOrange fluorochrome signals are the 3′ end of DDIT3 and the CytoGreen signals are the 5′ end of DDIT3 gene. (a) Demonstrates duplication of DDIT3 gene in low level. (b) DDIT3 break-apart probe (MetaSystems) showing evidence of gain of DDIT3 but no evidence of gene rearrangement. (c) FUS break-apart probe (MetaSystems) showing no evidence of FUS gene rearrangement.

• 

  Figure 6. Radiotherapy treatment plan using VMAT.

• 

  Figure 7. Postradiotherapy treatment field (Inner green area indicates tumour shrinkage after 28 fractions of RT).

• 

  Figure 8. CT of right shoulder postradiotherapy treatment (blue lines indicate tumour volume reduction) in frontal and sagittal planes.

• 

  Figure 9. Tumour size before and during (a–c) RT and (d) shoulder postsurgery.