The secretory activity of the submaxillary gland in the conscious rat is increased in the acute experiment when the secretion from one or more of the other salivary glands is prevented from reaching the oral cavity. In chronic experiments the weight of the submaxillary gland is augmented after duct ligation of other salivary glands. It seems likely that increased secretory activity as observed in the acute experiments, is the cause of this glandular hypertrophy.
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Elmér et al. (1969) studied this question.
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