Ca2+ stimulates rat liver mitochondrial glycerophosphate dehydrogenase activity at low, but not high, concentrations of its substrate, glycerophosphate.The midpoint for activation by Ca" is about lo" M. The Ca2+ effect was duplicated by Sr2+, but not by M$+.Hyperthyroidism increased total glycerophosphate dehydrogenase activity 12-fold, but did not significantly
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Wernette et al. (1981) studied this question.
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