Why the study?
What is the diagnostic yield of cardiovascular magnetic resonance in the screening of relatives to patients with arrhythmogenic right ventricular cardiomyopathy?
What is the diagnostic yield of cardiovascular magnetic resonance in the screening of relatives to patients with arrhythmogenic right ventricular cardiomyopathy?
CMR may aid ARVC family screening; leaves open optimal strategy and outcome impact.
Background: As a part of the revision of the Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Task Force Criteria in 2010 (2010 TFC), more specific cardiovascular magnetic resonance (CMR) parameters were included due to the ability to provide accurate information about anatomy and functionality of the right ventricle. All ARVC probands identified at our institution are offered family screening including CMR as a part of clinical screening for ARVC. The aim of this study was to evaluate the clinical value of CMR as a part of the screening program in relatives to patients with AVRC. Methods: The retrospective cohort study registered data from relatives to ARVC probands. All included subjects have had a CMR as a part of ARVC screening in the period from January 1st 2010 to September 1st 2016. Patient data were registered using the 2010 TFC and included results from non-invasive examinations (ECG, signal-averaged ECG, Holter, echocardiogram, CMR and genetics) and baseline information such as gender, age, and occurrence of cardiovascular symptoms. CMR scans were performed on a 1.5-Tesla scanner (Magnetom Avanto, Siemens, Germany) and all Images were analyzed independently using CVI42 (Circle Cardiovascular Imaging, Canada).
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Jurlander et al. (2017) studied this question.
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