Chemical Constituents from the Pericarp of Trewia nudiflora

Three new ent ‐atisane diterpenes, i.e. , 17‐hydroxy‐ ent ‐atisan‐19‐oic acid ( 1 ), 17‐hydroxy‐ ent ‐atisan‐19‐oic acid methyl ester ( 2 ), and 16 α ,17‐dihydroxy‐ ent ‐atisan‐19‐al ( 3 ), together with five known phenolic compounds, i.e. , gallic acid, ethyl gallate, protocatechuic acid, 3,4,4′‐tri‐ O ‐methylellagic acid, and α ‐tocopherol, and two other known compounds, i.e., trans ‐cinnamic acid and taraxerone, were isolated from the pericarp of Trewia nudiflora collected in Xishuangbanna, Yunnan Province, China. Their structures were elucidated by spectroscopic analysis including 1D‐ and 2D‐NMR. Trace amounts of maytansinoids were isolated by antifungal‐activity‐guided fractionation and determined by LC‐ESI‐MS analysis; they were prominent antifungal constituents in the pericarp of Trewia nudiflora.