Key result
Elevated wedged hepatic venous pressure identifies cirrhosis and correlates with varices and jaundice.
Observational
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The technic of occlusive venous catheterization has been applied to the liver. The pressure, measured in a small occluded hepatic vein and termed the wedged hepatic venous pressure, correlates well with the portal venous pressure in cats. An elevation of the wedged pressure in man, in the presence of a normal central venous pressure, is diagnostic of cirrhosis. This has proved to be of clinical value in the differentiation of intrahepatic from extrahepatic portal hypertension. The higher wedged hepatic venous pressures in cirrhosis are correlated with the presence of varices or jaundice, but not with the presence of ascites.
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Taylor et al. (1956) conducted an observational in Cirrhosis of the liver and noncirrhotic portal hypertension. Occlusive hepatic venous catheterization (wedged hepatic venous pressure measurement) vs. Normal liver and noncirrhotic portal hypertension was evaluated on Wedged hepatic venous pressure correlation with cirrhosis, portal hypertension type, varices, jaundice, and ascites. Occlusive hepatic venous catheterization measuring elevated wedged hepatic venous pressure with normal central venous pressure diagnosed cirrhosis and correlated with varices and jaundice.
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