The conventionally utilized mammographic signs of carcinoma only occasionally are indicative of minimal breast cancer. A new sign is described, which consists of the appearance of a new density in serial examinations. Of 30 patients who have exhibited this sign and who have had a biopsy, all have had either carcinoma or duct hyperplasia of borderline nature. Early mammographic examination is important in establishing a baseline against which subsequent studies can be compared.
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Martin et al. (1971) studied this question.
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