Key result
Whole-genome analysis of the G8P[14] rotavirus strain SI-2987/09 from a child with severe diarrhea revealed a genome constellation confirming zoonotic transmission, likely from ungulates.
Whole-genome analysis confirmed the zoonotic transmission of a G8P[14] rotavirus strain from an ungulate source to a child.
Suggests possible zoonotic sources in unexplained pediatric diarrhea; leaves open prevalence and surveillance needs for ungulate-derived strains.
The group A rotavirus strain SI-2987/09 was detected in a child with severe diarrhea. The whole-genome analysis revealed the G8-P[14]-I2-R2-C2-M2-A3-N2-T6-E2-H3 genome constellation, which reflects the zoonotic transmission of the strain most probably from the ungulate group. This was also confirmed by the high nucleotide identity to those animal rotavirus strains.
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Steyer et al. (2017) studied this question. Whole-genome analysis of the G8P[14] rotavirus strain SI-2987/09 from a child with severe diarrhea revealed a genome constellation confirming zoonotic transmission, likely from ungulates.
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