Vicious role of high calorie diet on organ metabolic syndrome induced thrombocyte, leukocyte and erythrocyte alterations

Metabolic syndrome is growing globally amongst all aged people. There is escalation of different oxidative stress param­eters, pro-inflammatory markers and pro-apoptotic markers which leads to vital organ metabolic syndrome. Hepatic and renal dysfunction due to intake of high calorie diet leads to decrease in platelet count. Likewise, during vital organ meta­bolic dysfunctions, there is increase in infiltration of leuko­cytes resulting in inflammation, while the erythrocyte count decreases, accompanied by increase in red blood cell distribu­tion width. Potential therapy for the vital organ dysfunctions due to metabolic syndrome can be thrombolytic therapy and transfusion of erythrocytes or erythropoietin. People need to rethink about their lifestyles, dietary habits, physical activ­ity and consumption of anti-oxidant foods containing green vegetables and fruits as well as Mediterranean diet to get rid from vital organ metabolic syndrome.