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January 1, 1984Journal of General Virology

Single Mutations at Many Sites within the DNA Polymerase Locus of Herpes Simplex Viruses Can Confer Hypersensitivity to Aphidicolin and Resistance to Phosphonoacetic Acid

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Authors

RHR. W. HonessInstitute of Virology of the Slovak Academy of SciencesDPD. J. M. PurifoyWellcome TrustDYDavid M. YoungAgency for Science, Technology and Research

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Cite This Study

Honess et al. (1984) studied this question.

synapsesocial.com/papers/6a730fb8bfabfe3aef60e646https://doi.org/10.1099/0022-1317-65-1-1
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Complementation between Phosphonoacetic Acid-resistant and -sensitive Variants of Herpes Simplex Viruses: Evidence for an Oligomeric Protein with Restricted Intracellular Diffusion as the Determinant of Resistance and Sensitivity1981 · 9 citations
  2. 2Genetic analysis of temperature-sensitive mutants which define the genes for the major herpes simplex virus type 2 DNA-binding protein and a new late function1983 · 28 citations
  3. 3Resistance of herpes simplex virus to acycloguanosine: role of viral thymidine kinase and DNA polymerase loci.1980 · 230 citations
  4. 4Collaborative complementation study of temperature-sensitive mutants of herpes simplex virus types 1 and 21978 · 133 citations