Why the study?
Does contrast two-dimensional echocardiography accurately measure left ventricular volume compared to standard contrast ventriculography?
Does contrast two-dimensional echocardiography accurately measure left ventricular volume compared to standard contrast ventriculography?
Contrast two-dimensional echocardiography underestimates left ventricular volume compared to ventriculography, but can reliably calculate ejection fraction and stroke volume using regression equations.
Contrast echo underestimates LV volumes; clinicians should interpret absolute volumes cautiously while researchers may rely on it for EF and stroke volume.
Simultaneous contrast two-dimensional echocardiograms and contrast ventriculograms were analyzed for 19 cardiac cycles in 6 patients. Ventriculographic volume was underestimated by 10 +/- 4.5% (p less than .001) by the contrast echocardiograms, despite good correlation (r = 0.88). Discrepancies could not be assigned to changes in volume between studies nor to a lack of precise endocardial definition. Simultaneous imaging demonstrated that the ultrasonic transducer was located 33 degrees cephalad to the cardiac apex. Although angiographic volume was severely underestimated, ejection fraction (r = 0.93) and stroke volume (r = 0.90) could be calculated from two-dimensional echocardiograms using regression equations.
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Barrett et al. (1982) studied this question.
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