Paroxysmal Atrial Fibrillation as the First Presentation of Coronary Artery Spasm

Atrial fibrillation (AF) is a common arrhythmia with increasing incidence and prevalence, associated with increased morbidity and mortality. The list of predisposing factors is extensive and includes coronary artery disease (CAD) as a significant trigger. Coronary spasm, an uncommon form of CAD, can very rarely present with AF. We report an adult male with no significant risk factors or family history, except for smoking, who presented with recurrent palpitations diagnosed and managed as paroxysmal AF. Within one year, the patient experienced recurrent attacks of acute chest pain associated with paroxysms of AF. Coronary angiography showed normal coronary anatomy, and coronary spasm was confirmed by a provocation test, which was associated with the development of arrhythmia. The calcium channel blocker (CCB) nifedipine and isosorbide mononitrate prevented the recurrence of these attacks. CAD should be managed as part of the holistic management of paroxysmal AF, and coronary artery spasms should be considered and treated with coronary dilators, especially CCBs.