Why the study?
Does the addition of CT perfusion imaging to CT angiography improve the detection of pulmonary emboli in a porcine model?
Population
6 pigs with an experimental pulmonary embolism model created by injecting type-A and type-B emboli
Comparison
CT angiography combined with CT perfusion image… vs CT angiography (CTA) alone
Design
Preclinical, Three independent observers
Key result
The combination of CTA and CTPI improved the sensitivity of detecting pulmonary emboli to 87% compared to 59% with CTA alone.
Authors
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Hypothesis-generating in porcine PE model; clinical adoption of CTA-CTPI requires prospective human validation.
Does the addition of CT perfusion imaging to CT angiography improve the detection of pulmonary emboli in a porcine model?
Absolute Event Rate: 87% vs 59%
CT perfusion imaging obtained by digital subtraction enhances the diagnostic accuracy of pulmonary embolism detection compared to CTA alone in a porcine model.
Chung et al. (2004) studied Pulmonary embolism (n=6). CTA and CTPI (computed tomography perfusion image) vs. CTA alone was evaluated on Sensitivity in the detection of pulmonary emboli. The combination of CTA and CTPI improved the sensitivity of detecting pulmonary emboli to 87% compared to 59% with CTA alone.
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