Describes a novel gravimetric technique for accurately measuring tissue volume changes, vascular capacitance, and transcapillary fluid movements in muscle.
May advance preclinical vascular research in muscle; leaves open human translation before any clinical consideration.
A technique is described by which changes of tissue volume of a muscle region enclosed in a plethysmograph can be followed in terms of water displacements measured with an electronic gravimetric transducer. Experimental tests show that the method provides accurate recordings of vascular capacitance responses and of transcapillary fluid movements.
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Grände et al. (1974) studied this question.
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