We performed seawater therapy on atopic dermatitis patients for 6 days with dolphins. The presence of the dolphins seemed to alleviate the pain patients experienced while bathing in seawater. The skin condition improved dramatically, and immunologically, serum IL-8 levels decreased but MIP-1α and eosinophil cationic protein did not change.
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Iíkura et al. (2001) studied this question.