Key result
Conservative medical management including total parenteral nutrition and jejunostomy feeding resulted in massive improvement in weight and symptoms over a nine-month follow-up in a 19-year-old female with Wilkie's syndrome.
Why the study?
Wilkie's syndrome is a rare cause of small bowel obstruction that can present atypically with unusually constant abdominal pain and weight loss.
Case Report (n=1)
Conservative management with total parenteral nutrition and jejunostomy feeding successfully treated a rare case of superior mesenteric artery syndrome in a young female presenting with severe weight loss and abdominal pain.
Answers are grounded in this paper and cite their sources.
May support initial conservative management in select Wilkie's cases; hypothesis-generating and should not yet change practice.
Wilkie's syndrome, also commonly known as superior mesenteric artery (SMA) syndrome, is an infrequent and rare cause of small bowel obstruction. It is caused by extrinsic compression of the duodenal segment of the intestine between the aorta and SMA, causing significant post-prandial abdominal pain and vomiting. The literature suggests the incidence of 0.01% to 0.3%. We present here an atypical presentation of SMA syndrome in which a young patient presented to our tertiary set-up with unusually constant abdominal pain and weight loss requiring invasive interventions.
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Waqar et al. (2019) conducted a case report in Wilkie's syndrome (Superior mesenteric artery syndrome) (n=1). Conservative medical management (Total parenteral nutrition and jejunostomy feeding) was evaluated on Symptom resolution and weight gain. Conservative medical management including total parenteral nutrition and jejunostomy feeding resulted in massive improvement in weight and symptoms over a nine-month follow-up in a 19-year-old female with Wilkie's syndrome.
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