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QTOF and Orbitrap techniques, as advanced mass spectrometry tools, show great potential in the field of pesticide residue analysis and degradation product identification. This paper reviews the application of these two techniques in pesticide residue analysis and degradation product identification. The principles and characteristics of QTOF and Orbitrap techniques are first introduced, including the advantages of high resolution, high sensitivity and high accuracy. Then, the applications of these techniques in different types of samples, including agricultural products, environmental samples and air samples, were explored. These studies demonstrate that QTOF and Orbitrap techniques can effectively detect and characterize low levels of pesticide residues and degradation products in complex samples. In addition, this paper summarizes the advantages and limitations of these techniques and suggests directions for future research. Taken together, the QTOF and Orbitrap techniques have important application prospects in pesticide residue analysis and degradation product identification and will provide strong support in areas such as food safety and environmental protection.
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Li et al. (2026) studied this question.
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