RECENTLY, the New York State (NYS) Department of Health sought the help of physicians after the intraoperative death of a 4-yr-old child was attributed to application of topical phenylephrine by the treating practitioners. A panel consisting of anesthesiologists, otorhinolaryngologists, intensivists, and pharmacists joined state authorities in reviewing this case to determine whether topical phenylephrine use in surgery could be an underrecognized source of morbidity.
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Groudine et al. (2000) studied this question.
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