Key result
Carotid B-mode ultrasound reliably matches QCA for vessel diameter, but shows poor agreement for lesion length.
Observational (n=75)
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BACKGROUND: To evaluate the correlation and agreement of the carotid artery landmarks necessary for carotid artery stenting obtained by B-mode ultrasonography (BMU), and by quantitative angiography (QCA) in patients with severe carotid artery stenosis. METHODS: In 75 patients undergoing carotid artery stenting, the distal common (CCA), proximal internal (ICA) carotid artery diameter, and lesion length were measured preoperatively by BMU, and intraoperatively by QCA. RESULTS: In 96% of the subjects, BMU imaging was adequate for interpretation. BMU and QCA Pearson correlation and Lin concordance coefficients were 0.75 (p < 0.001) and 0.959 (95% CI: 0.930 - 0.996), respectively, for CCA diameter, 0.88 (p < 0.001) and 0.954 (95% CI: 0.928-0.983), respectively, for ICA diameter, and 0.62 (p < 0.001) and 0.734 (95% CI: 0.719-0.760), respectively, for lesion length, with a 0.765 bias correction factor and a wider data scatter by Bland Altman plots showing shorter lesion length by BMU than by QCA. CONCLUSIONS: In patients with carotid artery stenosis, BMU can provide reliable distal CCA and proximal ICA diameters in comparison with QCA, whereas lesion length measured by BMU has an acceptable correlation, but a poor agreement with QCA.
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Harmon et al. (2014) conducted an observational in Severe carotid artery stenosis undergoing carotid artery stenting (n=75). Preoperative B-mode ultrasonography (BMU) vs. Intraoperative quantitative angiography (QCA) was evaluated on Correlation and agreement of distal common carotid artery (CCA) diameter, proximal internal carotid artery (ICA) diameter, and lesion length (Lin concordance 0.959 for CCA, 0.954 for ICA, 0.734 for lesion length, 95% CI 0.930-0.996, p=<0.001). B-mode ultrasonography agreed reliably with QCA for CCA (concordance 0.959) and ICA (0.954) diameters, but had poor agreement for lesion length (0.734; 95% CI 0.719-0.760).
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