The duration of the DNA synthesis period in human biopsy specimens of normal and neoplastic cell populations from the larynx, trachea, bronchus, and esophagus of 13 patients has been estimated by a TdR-3H, -14C double-labeling method in vitro. A model for determining potential tissue doubling times in these tissues is presented. Data from these studies provide information concerning human cell proliferation.
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Jacob I. Fabrikant (1970) studied this question.