Key result
COVID-19-related school closing significantly increased alanine aminotransferase (from 53.0 to 74.7 U/L) and body mass index in pediatric patients with obesity.
Why the study?
The indirect effects of COVID-19 pandemic social distancing and reduced physical activity on children and adolescents with obesity needed exploration.
Does COVID-19-related school closing aggravate obesity and glucose intolerance in pediatric patients with obesity?
Population
90 patients aged between 6- and 18-year-old diagnosed with obesity
Comparison
Pre-school closing period vs school closing period
Authors
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May warrant closer monitoring of weight and glucose in obese youth during activity restrictions; leaves open whether targeted interventions mitigate effects.
Observational (n=90)
No
Does COVID-19-related school closing aggravate obesity and glucose intolerance in pediatric patients with obesity?
Absolute Event Rate: 74.7% vs 53%
p-value: p=<0.001
COVID-19-related school closures and resulting physical inactivity significantly worsened obesity, lipid profiles, and liver enzymes in pediatric patients, with a pronounced increase in HbA1c among those with NAFLD.
Kim et al. (2021) conducted an observational in Pediatric obesity (n=90). COVID-19-related school closing vs. Pre-school closing period was evaluated on Alanine aminotransferase (ALT) level (p=<0.001). COVID-19-related school closing significantly increased alanine aminotransferase (from 53.0 to 74.7 U/L) and body mass index in pediatric patients with obesity.
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