Antimicrobial constituents of the leaves ofAcalypha wilkesiana and Acalypha hispida

An Erratum for this article has been published in Phytotherapy Research 14(8), 2000, 661. An activity directed fractionation of a 50% aqueous ethanol extract of A. wilkesiana and A. hispida leaves resulted in the isolation of gallic acid, corilagin and geraniin as the compounds responsible for the observed antimicrobial activity. Quercetin 3-O-rutinoside and kaempferol 3-O-rutinoside were also isolated from the inactive fraction of A. hispida. The structures were established by permethylation, 2D - NMR (1H and 13C) and MS data.