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July 1, 2026Journal of the Faculty of Medicine BaghdadOpen Access

Non-Polio Enteroviruses in Acute Flaccid Paralysis: Analysis of Surveillance in Iraq from 2018 to 2024

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Why the study?

To determine the prevalence, epidemiologic trends, and clinical features of non-polio enteroviruses among children with acute flaccid paralysis in Iraq to improve surveillance sensitivity and guide public health measures.

Population

Children with acute flaccid paralysis in Iraq from 2018 to 2024

Design

Surveillance system analysis

Key result

Non-polio enteroviruses were detected in 10.5% of acute flaccid paralysis cases in Iraqi children under 15 years, with significantly higher positivity in younger children and an association with residual weakness.

Authors

NNNadia A. NasirMMMurad Th. MehmoudMAmuhi K. AL-Janabi

Discussion

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Overview

AFP surveillance detects ongoing NPEV circulation; leaves open serotype-specific risks and interventions.

Study Design

Type

Observational (n=5,662)

Multicenter

Yes

Structured PICO

P
Population
5,662 children under 15 years of age with acute flaccid paralysis in Iraq, evaluated between 2018 and 2024 to determine the prevalence and clinical features of non-polio enteroviruses.
O
Outcome
Prevalence, epidemiologic trends, and clinical features of non-polio enteroviruses (NPEVs)

Non-polio enteroviruses are a significant cause of acute flaccid paralysis in Iraqi children, particularly those aged 1-2 years, and are associated with residual weakness but lower mortality compared to NPEV-negative cases.

Limitations

  • NPEV isolates were not serotyped or genetically defined, precluding assessment of strain-specific epidemiology.
  • Analyses were confined to AFP cases and may not be representative of NPEV circulation in the general population.
  • The COVID-19 pandemic may have impacted surveillance activities and interfered with case detection.
  • NPEV isolates were not serotyped or genetically defined, precluding assessment of strain-specific epidemiology
  • Analyses were confined to AFP cases and may not be representative of NPEV circulation in the general population
  • COVID-19 pandemic may have impacted surveillance activities and interfered with case detection

Cite This Study

Nasir et al. (2026) conducted an observational in Acute Flaccid Paralysis (n=5,662). Non-polio enteroviruses (NPEV) vs. NPEV-negative acute flaccid paralysis cases was evaluated on Prevalence of non-polio enteroviruses in acute flaccid paralysis cases. Non-polio enteroviruses were detected in 10.5% of acute flaccid paralysis cases in Iraqi children under 15 years, with significantly higher positivity in younger children and an association with residual weakness.

synapsesocial.com/papers/6a734f154e82b1a46ac679adhttps://doi.org/10.32007/jfacmedbaghdad3246
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Detection of non-polio and polio enteroviruses in Acute Flaccid Paralysis surveillance in Turkey2021 · 3 citations
  2. 2Epidemiology and clinical findings associated with enteroviral acute flaccid paralysis in Pakistan2007 · 62 citations
  3. 3Clinical profile of acute flaccid paralysis2016 · 2 citations
  4. 4Surveillance of Acute Flaccid Paralysis (AFP) in Greece: 2008–20242025 · 2 citations
  5. 5Impact of COVID-19 Pandemic on Global Poliovirus Surveillance2020 · 39 citations