Key result
Thyroid dysfunction unfavorably impacts chronic heart failure prognosis, highlighting the potential benefit of restoring euthyroidism.
Answers are grounded in this paper and cite their sources.
Thyroid hormones have relevant activity at cardiac and vascular level, by influencing heart rate, myocardial excitability as well as inotropic and lusitropic status, systemic vascular resistance and blood pressure. Moreover, they interact with neuro-hormonal systems such as sympathetic nervous system and renin-angiotensin-aldosterone system thus also indirectly influencing cardiovascular function. Due to these effects, both hypothyroidism and hyperthyroidism, either in their overt or subclinical forms, can have an unfavourable impact in the setting of cardiovascular diseases. The aim of this review is to focus on the prognostic consequences of thyroid disorders in heart failure patients. Moreover, the therapeutical approach and the possible beneficial effects of restoring euthyroidism are reviewed.
No takes yet. Share an insight, caveat, or question.
Triggiani et al. (2013) conducted a review in Chronic heart failure and thyroid disorders. Restoring euthyroidism / thyroid disorder management was evaluated. Overt and subclinical hypothyroidism and hyperthyroidism unfavorably impact chronic heart failure prognosis, with this narrative review examining therapeutic restoration of euthyroidism.
Synapse has enriched 10 related papers. Consider them for comparative context: