Why the study?
Does inhibition of sympathetic nerve discharge alter digital circulation pressure and flow differently in hypertensive compared to normotensive subjects?
Population
36 hypertensive and 23 normotensive subjects (total n=59)
Comparison
Inhibition of sympathetic nerve discharge via… vs Baseline measurements and normotensive control…
Design
Cross-sectional
Authors
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Structural changes may drive hypertensive digital narrowing more than tone; leaves open targeted interventions pending prospective trials.
Does inhibition of sympathetic nerve discharge alter digital circulation pressure and flow differently in hypertensive compared to normotensive subjects?
This early physiological study suggests that structural changes (sclerosis or edema) rather than increased smooth muscle tone primarily cause intrinsic digital vascular narrowing in hypertension.
Mendlowitz et al. (1957) studied this question.