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The airway-to-lung size discrepancy on computed tomography (CT-assessed dysanapsis) highlights a lifelong risk for developing lung diseases. This study demonstrated that the spirometric index of the dysanapsis ratio can be used for estimating CT-assessed dysanapsis of the entire central airway tree from the trachea to subsegmental airways, whereas a novel index, peak expiratory flow/forced vital capacity (PEF/FVC), can be used for estimating CT-assessed dysanapsis of the extrapulmonary airways (the trachea, main bronchus, and bronchus intermedius).
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Shimada et al. (2025) studied this question.
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