Why the study?
Is there a higher prevalence of hepatitis C virus in patients with myocarditis and dilated cardiomyopathy compared to those with noninflammatory cardiac diseases?
Is there a higher prevalence of hepatitis C virus in patients with myocarditis and dilated cardiomyopathy compared to those with noninflammatory cardiac diseases?
Hepatitis C virus does not appear to be an important causal agent for myocarditis and dilated cardiomyopathy, challenging findings from previous smaller studies.
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No support for HCV as causal in DCM/myocarditis; challenges smaller prior studies yet leaves role open for prospective confirmation.
We investigated the prevalence of hepatitis C virus in patients with dilated cardiomyopathy (DCM) and myocarditis in comparison to a control group of patients suffering from noninflammatory cardiac diseases such as aortic stenosis. In contrast to the results of previous studies on small numbers of patients, no significant difference in the prevalence of hepatitis C infections was observed. Our data suggest that HCV is not an important causal agent for myocarditis and DCM.
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Grumbach et al. (1998) studied this question.
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