Biophysical study reveals surfactant-induced membrane curvature and gradual solubilization in supported lipid bilayers, indicating mechanisms for viral and cellular disruption.
gradually disturbed the SLB morphology owing to spontaneously induced curvature changes in the SLB upon incorporation. This solubilized the lipid layers with slower kinetics as compared to that with the SDS detergent. Our findings provide a clue to the scientific understanding of the influence of additives on lipids during viral and cell disruption, which has potential implications in toiletry and cosmetics industries.
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Hanzawa et al. (2025) studied this question.
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