in sensitivity analyses extending the incubation period to 72 hours (OR, 2.8; 95% CI, 1.2-6.3).Trends in other areas did not reach statistical significance, and the effect was not significant in an adjusted hospitalwide analysis.Subsequent investigation revealed that cleaning practices for the scanner table of the CT-ED had not yet been updated to match the standardized methods applied in other radiology suites.Discussion | In a large university hospital, passing through the CT-ED within 24 hours after a patient with C difficile had been there was associated with increased risk of developing CDI.Our novel analytic methods identified a previously undiscovered opportunity for real-world practice change.We continue to monitor the success of improved cleaning practices implemented as a result of this study.Leveraging EHR data for spatial and temporal analytics may be a widely applicable strategy for infection control and quality improvement at other institutions and for other infectious diseases.
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Tessler et al. (2017) studied this question.