Five dipeptidase activities in the mucosa of the rat small intestine have been determined and characterized by the aid of a new spectrophotometric assay method.The distribution of the dipeptidase activities along the gastrointestinal tract has been investigated. The activities were low in the stomach, the cecum and the large intestine, while high activities were found along the whole length of the small intestine with the maximum localized to its middle part. The relation of our present findings to previous observations about the rat intestinal dipeptidases has been discussed. Some differences with respect to both their properties and their distribution were observed in com‐ parison with the dipeptidases of the pig intestinal mucosa.
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Josefsson et al. (1966) studied this question.
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