Why the study?
Secondary forms and hypertension-mediated organ damage may differ between younger and older hypertensive patients.
Does the frequency of hypertension-mediated organ damage and secondary hypertension differ between older (≥65 years) and younger hypertensive patients?
Does the frequency of hypertension-mediated organ damage and secondary hypertension differ between older (≥65 years) and younger hypertensive patients?
Extensive screening for hypertension-mediated organ damage in older patients may be of limited value as nearly all have at least one, but screening for secondary aetiologies remains important as over a quarter have a secondary form.
Answers are grounded in this paper and cite their sources.
Exploratory cohort data in older hypertensives; leaves open whether age-tailored HMOD or secondary-form screening improves outcomes.
BACKGROUND: Secondary forms and hypertension-mediated organ damage (HMOD) may differ between younger and older hypertensive patients. The aim of the present study was to explore the specificity of HMOD and secondary forms in patients ≥ 65 years in comparison to younger ones in a contemporary cohort. METHODS: We analysed 938 patients recruited between 2004 and 2014 (Cardiology department, Croix-Rousse Hospital, Lyon) who had at baseline HMOD and secondary forms screening among them 190 were ≥ 65 years. Among older patients, 3.2% were treated with adrenalectomy and 6.3% with percutaneous transluminal renal angioplasty. CONCLUSION: Extensive screening of HMOD in older patients may be questionable as nearly all patients had one; aetiology must however be explored as a third of older patients had a secondary form.
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Thiolliere et al. (2022) studied this question.
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