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The postoperative analgesic management of a patient who was intolerant of morphine and pethidine is described. An epidural infusion of fentanyl up to 1 microgram/kg/hour was ineffective for analgesia in the first 18 hours. Subsequently, 50-micrograms boluses and an infusion of 0.5 microgram/kg/hour sufentanil provided satisfactory analgesia with minimal side effects for 28 hours.
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Madej et al. (1987) studied this question.
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