Some characteristics and allopurinol release of carrageenan/ allopurinol films using polyethylene oxide as a dispersion aid agent

This paper presents the effect of carrageenan (CG) on some characteristics and drug release of allopurinol in the presence of polyethylene oxide (PEO) as a dispersion aid agent. The samples were prepared in film shape by solution method, in which, the content of PEO was changed from 1 wt.% to 5 wt.% and the content of allopurinol was fixed at 10 wt.% in comparison with carrageenan weight. FTIR , FESEM, UV-Vis methods were used to evaluate characterizations and morphology of CG/PEO/allopurinol films.