Why the study?
Patient outcomes in emergency general surgery may be influenced by time of day, with prior studies suggesting worse nighttime outcomes, prompting evaluation of differences in damage control laparotomy utilization and mortality.
Does nighttime surgery affect all-cause inpatient mortality and DCL rates in patients undergoing emergent exploratory laparotomy compared to daytime surgery?
Does nighttime surgery affect all-cause inpatient mortality and DCL rates in patients undergoing emergent exploratory laparotomy compared to daytime surgery?
Nighttime emergent exploratory laparotomy is associated with higher damage control laparotomy utilization, likely due to higher patient acuity.
Nighttime EGS may require adjusted resource allocation; leaves open whether timing independently affects DCL use or mortality.
Background Patient outcomes in emergency general surgery (EGS) may be influenced by the time of day, with prior studies suggesting worse outcomes for nighttime procedures. This study examines differences in damage control laparotomy (DCL) utilization and mortality between daytime and nighttime emergent laparotomies. Methods Retrospective cohort study from January, 2015 to December, 2023 of patients undergoing emergent exploratory laparotomy during either daytime (7:00 AM-5:00 PM) or nighttime (5:00 PM-7:00 AM) was performed. The primary outcome was all-cause inpatient mortality. Secondary outcomes included DCL rates, complications, critical care metrics, and hospital length of stay. Between-group differences were assessed, and multivariate logistic regression was used to evaluate the effect of nighttime presentation on DCL and mortality. Results Among 1279 patients, 710 received daytime surgery (56%). Nighttime patients (n = 569, 44%) had higher ASA class 5 proportions (8.6% vs 4.8%, P = .0062) and greater intraoperative vasopressor use (62% vs 52%, P = .0350). Damage control laparotomy was more frequent at night (50.4% vs 38.7%). Mortality was higher for nighttime cases (18.3% vs 14.1%), independent of treatment DCL. Nighttime surgery was associated with significantly greater rates of ICU admission, mechanical ventilation, and vasopressor use, but durations of these therapies were not significantly different between groups. Nighttime surgery showed an odds ratio of 1.42 for receiving DCL (95% CI 1.06-1.90, P = .017), but it was not clearly associated with mortality. Conclusions For EGS patients, nighttime surgery is associated with higher DCL utilization and mortality compared to daytime surgery. These findings are likely due to higher patient acuity and hemodynamic instability at night.
No takes yet. Share an insight, caveat, or question.
Duncan et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: