Answers are grounded in this paper and cite their sources.
Macrophages incubated with products (lymphokines) secreted by stimulated spleen cells produced collagenase. Active lymphokines were obtained both from mitogen- and antigen-stimulated lymphocytes. These observations suggest that the degradation of collagen in chronic inflammatory lesions may be caused by macrophage collagenase.
No takes yet. Share an insight, caveat, or question.
Wahl et al. (1975) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: