Probable Clinical Utility of Cation Exchange Resins

The data which have been presented in the pre-vious papers clearly indicate that the carboxylic cation exchange resins in the hydrogen, am-monium, sodium, and potassium forms individually or in combinations increase the stool excretion of sodium and potassium in man and dog (1-4). In the amounts administered however, 20 to 60 g./ day, there was only a limited absolute increase in the stool content of sodium and potassium. The in vivo efficiency of these exchangers was usually 1 meq. of sodium or less removed per gram of resin ingested when the diet contained sodium. In addition, potassium excretion per gram of the resin was usually about 50 % greater than sodium. Although stool sodium was largest during the ad-