Present Rôle of the Artificial Kidney in Clinical Therapy

Article1 July 1950PRESENT RÔLE OF THE ARTIFICIAL KIDNEY IN CLINICAL THERAPYJOHN P. MERRILL, M.D.JOHN P. MERRILL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-1-100 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough earlier efforts at the production of an apparatus for the extracorporeal dialysis in blood had met with some success, it remained for Kolff1in Holland and, simultaneously, Murray2in Canada to perfect the first apparatus for effective clinical use. Since that time modifications of these devices have been constructed and used by others in this country and Europe.3, 4Our experience has been with a modified form of the Kolff apparatus which we have used for the past two years in a series of 120 clinical trials. Modifications of the technic and new devices described elsewhere5, 6have increased...Bibliography1. Kolff SJ: New ways of treating uremia, 1947, J. and A. Churchill, Ltd., London. Google Scholar2. MurrayDelormeThomas GEN: Development of an artificial kidney: experimental and clinical experiences, Arch. Surg. 55: 505-522, 1947. CrossrefMedlineGoogle Scholar3. SkeggsLeonards LTJR: Studies on an artificial kidney: I. Preliminary results with a new type of continuous dialyzer, Science 108: 212-213, 1948. CrossrefMedlineGoogle Scholar4. Alwall N: On the artificial kidney. I. Apparatus for dialysis of the blood in vivo, Acta med. Scandinav. 128: 317-323, 1947. CrossrefMedlineGoogle Scholar5. MerrillThornWalterCallahanSmith JPGWCWEJLH: The use of an artificial kidney. I. Technique, J. Clin. Invest. 29: 412, 1950. CrossrefMedlineGoogle Scholar6. MerrillSmithCallahanThorn JPSEJGW: The use of an artificial kidney. II. Clinical aspects, J. Clin. Invest. 29: 425, 1950. CrossrefMedlineGoogle Scholar7. Strauss MB: Acute renal insufficiency due to lower nephron nephrosis, New Eng. J. Med. 239: 1693, 1948. CrossrefGoogle Scholar8. EmersonBinkley KOF: Effect of administration of essential amino acids on utilization of dietary protein in malnutrition among war casualties, J. Clin. Invest. 25: 184, 1946. CrossrefGoogle Scholar9. MerrillLevineSomervilleSmith JPHCWS: III. Clinical recognition and treatment of acute potassium intoxication, Ann. Int. Med. In press. Google Scholar10. MerrillGoodale JPW: Unpublished observations. Google Scholar11. Borst JG: The cause of hyperchloremia and azotemia in patients with recurrent massive hemorrhage from peptic ulcer, Acta med. Scandinav. 128: 250, 1947. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Presented before the 31st Annual Session of the American College of Physicians, Boston, April 19, 1950.This work was done in part during the tenure of a research fellowship of The American Heart Association.From the Department of Medicine, Harvard Medical School, and the Medical Clinic, Peter Bent Brigham Hospital, Boston, Mass.This work was aided in part by a grant from the National Heart Institute, U. S. Public Health Service, and in part by a grant from the office of the Surgeon General, U. S. Army. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byStörungen im KaliumstoffwechselClinical Experience with the Skeggs-Leonards Artificial KidneyTREATMENT OF BROMISM WITH THE ARTIFICIAL KIDNEY*JOHN P. MERRILL, JOHN M. WELLERThe Changing Emphasis in the Management of Renal DiseasesThe Artificial KidneyThe Artificial Kidney 1 July 1950Volume 33, Issue 1Page: 100-107KeywordsBloodClinical trialsFellowshipsHeartHospital medicineKidneysMedical dialysisMedical servicesSurgeons ePublished: 1 December 2008 Issue Published: 1 July 1950 PDF downloadLoading ...