Why the study?
Does treatment for Hodgkin's disease increase the risk of late lethal second events compared to the general population?
Population
2980 patients treated for Hodgkin's disease during 1970-1995 with long-term follow-up in a single Mexican…
Comparison
Treatment for Hodgkin's disease vs General population
Design
Cohort
Follow-up
> 4 years
Authors
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Long-term Hodgkin survivors warrant ongoing surveillance for second cancers and cardiac events; leaves open whether modern regimens attenuate this excess mortality.
Does treatment for Hodgkin's disease increase the risk of late lethal second events compared to the general population?
Treatment for Hodgkin's disease significantly increases the risk of late fatal second neoplasms and cardiac events compared to the general population, emphasizing the need for less toxic therapeutic regimens.
Avilés et al. (2000) studied this question.
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