November 1, 1986Pacing and Clinical Electrophysiology
Twelve Years of Clinical Experience with Lithium Pulse Generators
Why the study?
What is the long-term clinical performance and longevity of lithium pulse generators?
Population
9,651 lithium pulse generators implanted at registry hospitals since 1973
Comparison
Lithium pulse generators vs Lithium iodine compared to lithium cupric sulfide
Design
Cohort
Follow-up
Up to 12 years
Authors
Discussion
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Member takes
Implication
Reassures on lithium pacemaker durability in practice; extends observational longevity data but leaves battery selection open for prospective study.
Structured PICO
What is the long-term clinical performance and longevity of lithium pulse generators?
P
Population
9,651 lithium pulse generators implanted at registry hospitals since 1973
I
Intervention
Lithium pulse generators (lithium iodine and lithium cupric sulfide)
C
Comparator
Lithium iodine compared to lithium cupric sulfide
O
Outcome
Actuarial survival (longevity) of pulse generators at 5, 7, and 10 years
Lithium iodine and lithium cupric sulfide batteries are safe, long-term energy sources for pacemakers, demonstrating 62% survival at 10 years.
Limitations
- Impact of reduced battery size and dual chamber pacing on performance parameters is unknown
Cite This Study
Hauser et al. (1986) studied this question.