Psychosocial correlates of health-related quality of life among people living with HIV in China

OBJECTIVES: The current study aims to examine associations between psychosocial factors and health-related quality of life (HRQoL) and the role of psychological resilience in mediating the relationship between perceived social support (PSS) and HRQoL. DESIGN: A cross-sectional study was conducted among people living with HIV (PLHIV) in Guangxi, China. A sample of 2987 PLHIV (1876 men and 1111 women) was included in the current analysis. METHODS: Hierarchical multiple regression models were employed to assess the association of HRQoL with stigma, three types of PSS (informational, emotional and tangible), and resilience as well as to identify the possible role of resilience in mediating the effect of PSS on HRQoL RESULTS:: HRQoL was negatively associated with stigma (β = -0.27, P < 0.001), but positively associated with emotional PSS (β = 0.13, P < 0.001). After resilience was added to the model, HRQoL remained negatively associated with stigma (β = -0.20, P < 0.001), but positively associated with resilience (β = 0.38, P < 0.001). A mediating effect of resilience was found between emotional PSS and HRQoL (Sobel's Z = 16.87, P < 0.001). CONCLUSION: Interventions that consider enhancing resilience through building social support, especially emotional social support, will likely improve HRQoL among PLHIV.