Aim; This study aims to investigate the seroprevalence of Toxoplasma gondii in psychiatric patient patient groups. Methods; To define anti- Toxoplasma gondii IgG and anti- Toxoplasma gondii IgM antibodies seropositivity and determine the seroprevalence of toxoplasmosis in patients presenting at the Psychiatry outpatient clinic of Healthcare Application and Research Hospital, Sivas Cumhuriyet University were use ELISA method. 175 psychiatric patients (65 patients with schizophrenia, 46 Depression and 64 Bipolar Affective Disorder) aged from 18-80 years old and samples from 100 the same age range healthy individuals as a control group. Results; Anti-Toxoplasma gondii IgG antibody was found positive in 33 (50.76%) of 65 schizophrenia patients, in 24 (52.17%) of 46 depression patients and 30 (46.87%) of 64 BAD patients. This rate was determined as 25 (25%) in the control group. anti-Toxoplasma gondii IgM antibody was found in 4 (6.15%) of 65 patients with schizophrenia and 5 (7.81%) of BAD patients. anti-Toxoplasma gondii IgM antibody was not found in 46 depression patients. This rate was determined as 1 (1%) in the control group. Conclusions; The prevalence of Toxoplasma gondii infection in patients with schizophrenia and bipolar disorder was significantly higher compared to the control group. Measurement of anti-Toxoplasma antibodies in psychiatric disorders enables the evaluation of the disease and the timely initiation of treatment. It was concluded that Toxoplasma gondii infection may be a risk factor in patients with psychiatric disorders.
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Özpınar et al. (2020) studied this question.
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