Primary Paroxysmal Myoglobinuria

SINCE the first case of primary paroxysmal myoglobinuria was reported by Meyer-Betz1 in 1911 more than 60 cases have appeared in the literature. The frequency of diagnosis appears to be increasing; however, the pathogenesis of the disease remains obscure. The first case of primary myoglobinuria treated at the Indiana University Medical Center was in 1957.2 Recently, a second patient with the disease was seen. Both cases were similar in the severity of illness, and both demonstrated some of the difficulties of diagnosis and treatment.Case ReportA 3-year-old boy with the dual complaints of muscle pain and weakness associated with . . .