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The majority of acute promyelocytic leukemia (APL) cases are characterized by the expression of the chimeric fusion gene PML-RARA . Although the PML-RARA fusion gene is detected in more than 95% of APL cases, RARA has also been found to fuse with other partner genes in some APL variants. To date,
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Kondo et al. (2008) studied this question.
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