Short-Term Intensive Insulin Therapy in Newly Diagnosed Type 2 Diabetes

The recent report by Ryan et al. (1) demonstrated that in newly diagnosed type 2 diabetes, a short course of intensive insulin therapy successfully laid a foundation for long-term good glycemic control and suggested that the only predictors that could be maintained on diet alone in the long term were those concerned with the ease with which glycemic control could be achieved. We agree with their strategy of short-term intensive insulin therapy to restore β-cell insulin secretion and/or insulin action that is impaired by glucose …